Pain may be a usual situation of patients with chronic wounds. Wound infection can prolong healing and cause and deepen wound pain. The basic principle reason is that the inflammatory reaction caused over the infection causes the wound pain. This response ends in causing the tissue injury due to the release of inflammatory mediators and accelerates the creation of enzymes and free radicals. The main contributor to wound pain is dressing changes. Pain management should include pain analysis before, throughout and once every dressing modification to form sure that the affected person’s pain is managed with success. Such progressing assessment will permit healthcare specialists to identify any causes which will be altered or avoided to chop back pain.